Friday, November 15, 2013

Creating Better Protein Through the Process of Evolution

A protein based drug has been developed through the concept of evolution. This drug specifically is targeted to help prevent heart disease. Specific protein functions were targeted and put through the process of evolution and time. This process would begin by having a lot of variations of the targeted cell and then picking the one variant that has evolved the best and then repeating the process again until you have a protein that carries the function you want. An international team along with the University of Leicester and Cambridge has been trying to develop this method to treat heart problems such as inflammation through the use of these ligand-trap protein. It is said that these evolutionary engineered proteins have good future applications in chemicals, pharmaceuticals and agriculture. 

5 comments:

  1. This is interesting. How long is this process? When I think of the term evolution, I think of hundreds of years. Interesting nonetheless.

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  2. What a brilliant idea. Humans have been breeding dogs since forever, so why not proteins? I would also have liked to know how long this process takes, without having to click on the link to the article. Interesting nonetheless.

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  3. I wonder if this protein or different proteins can treat other things besides heart disease?

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  4. This is very interesting. There are so many different methods of coming about a new treatment; forward genetics, knockout genetics, and now evolutionary engineered proteins.

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  5. How do they evolve a protein? It doesn't replicate! Don't make the reader rely on your link for the most essential elements of a story.

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